Abstract
To understand changes in the heart with congenital defects, it is necessary first of all to study the patterns of its embryonic development. The article highlights the main stages in the formation of the doctrine of cardiac embryology, emphasizing the importance of studying the history of the development of ideas about the formation and regeneration of organs and tissues in phylo- and ontogenesis, including resolving the issue of the place and role of genetic and epigenetic factors in normal conditions and in congenital defects development. The modern doctrine of embryogenesis of the heart became possible only with the development of the cellular theory of the structure of living organisms, according to wich the integrity and individualization of cells is not inferior to the integrity of a multicellular organism, and in some respects even exceeds it.
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About the authors
Roman A. Serov, Dr. Med. Sci., Professor, Head of Department;
ORCID
