Abstract
We carried out clinicomorphologic analysis of heart rhabdomyoma in newborns. It was demonstrated that tumor has the shape of a node growing from left ventricle wall associating with mitral annulus obstruction. It results in early manifestation of heart failure signs. It was also observed that heart rhabdomyoma may associate with multiple congenital heart and vascular defects. We suppose that there is the same pathogenic mechanism for development of heart rhabdomyoma and developmental defects which is proved by peculiar connective-tissue reactions. It seems that the acquired data will be used for early life-time diagnosis and treatment of primary heart tumors associated with connective-tissue heart dysplasias.
References
1. Белозеров, Ю. М. Клинические маски рабдомиомы сердца у детей / Ю. М. Белозеров // Российский вестник перинатологии и педиатрии. - 2003. - № 2. - С. 15-18.
2. Демин, В. Ф. Значение соединительнотканных дисплазий в патологии детского возраста / В. Ф. Демин, С. О. Ключников, М. А. Ключникова // Вопросы современной педиатрии. - 2005. - № 1. - С. 50-56.
3. Земцовский, Э. В. Соединительнотканные дисплазии сердца / Э. В. Земцовский. - СПб., 2000.
4. Харенко, И. В. Ультразвуковая картина опухолей сердца у детей в периоды новорожденности и грудного возраста / И. В. Харенко, Д. К. Волосников //Ультразвуковая и функциональная диагностика. - 2005. - № 4. - С. 97-101.
5. Becker, A. E. Primary heart tumors in the pediatric age group: a review of salient pathologic features relevant for clinicians / A. E. Becker // Pediatr. Cardiol. - 2000. - Vol. 21. - P. 317-323.
6. Ganame, J. Different deformation patterns in intracardiac tumors / J. Ganame, J. Dhooge, L. Mertens // Eur. J. Echocardiography. - 2005. - Vol. 6. - P. 461-464.
7. Liddicoat, J. Tumors of the hearts / J. Liddicoat, M. Gillinov // Sabiston and Spenser Surgery of the Chest. - 7th ed. - Philadelphia, 2005. - P. 1741-1748.
8. Padalino, M. A. Surgically treated primary cardiac tumors in early infancy and childhood / M. A. Padalino, C. Basso, O. Milanesi et al. // J. Thorac. Cardiovasc. Surg. - 2005. - Vol. 129. - P. 1358-1363.
9. Stiller, B. Primary cardiac tumours: when is surgery necessary / B. Stiller, R. Hetzer, R. Meyer // Eur. J. Cardiothorac. Surg. - 2001. - Vol. 20. - P. 1002-1006.
10. Yu, K. Epidemiological and pathological characteristics of cardiac tumors: a clinical study of 242 cases / K. Yu, Y. Liu, H. Wang et al. // Interactive Cardiovasc. Thoracic. Surg. - 2007. - Vol. 6. - P. 636-639.
