Influence of congenital heart disease on the developing fetal brain

Authors: Marzoeva O.V., Sipchenko E.V., Leonova E.I., Gasanova R.M., Yarygina T.A.

Company: ¹ Bakoulev National Medical Research Center for Cardiovascular Surgery, Moscow, Russian Federation
² National Medical Research Center of obstetrics, gynecology and perinatology named after acad. V.I. Kulakov, Moscow, Russian Federation

Cite as: Marzoeva O.V., Sipchenko E.V., Leonova E.I., Gasanova R.M., Yarygina T.A. Influence of congenital heart disease on the developing fetal brain. Children’s Heart and Vascular Diseases. 2022; 19 (1): 34–41 (in Russ.). DOI: 10.24022/1810-0686-2022-19-1-34-41

Received / Accepted: 17.09.2021 / 05.12.202

Keywords: prenatal diagnosis congenital heart disease brain

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Abstract

The purpose of this review was to study the Russian and foreign literature on the effect of congenital heart disease on the developing fetal brain, assessing the degree of risk of developing neurological pathology in such a child in the future. The results obtained are confirmed both by instrumental methods of studying the brain (in particular, magnetic resonance imaging) and by clinical manifestations and indicate that in a large percentage of cases, newborns with heart disease also have a pathology of the central nervous system, which radically changes parent counseling concept. They also indicate the need for a more detailed study of the fetal brain in the presence of a heart defect.

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About the authors

Ol’ga V. Marzoeva, Cand. Med. Sci., Ultrasound Doctor; ORCID
Elena V. Sypchenko, Cand. Med. Sci., Ultrasound Doctor; ORCID
Elena I. Leonova, Ultrasound Doctor; ORCID
Rena M. Gasanova, Dr. Med. Sci., Research Associate, Cardiologist; ORCID
Tamara A. Yarygina, Cand. Med. Sci., Ultrasound Doctor; ORCID

Chief Editor

Konstantin V. Shatalov
MD, PhD, DSc, Professor
Bakoulev National Medical Research Center for Cardiovascular Surgery

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