Abstract
Introduction. As the result of intracardiac hemodynamics in utero, TAPVC patients have diminished LV size and volume after birth. The influence of intracardiac hemodynamics in utero at systolic and diastolic function of LV in the long-term period after surgical correction should be studied.
Objective: evaluation of systolic and diastolic function of left ventricle in the long-term period after surgical correction of total anomalous pulmonary venous connection. Material and methods. There were included 20 patients after TAPVC surgery. The systolic and diastolic LV function was evaluated at all included patients in the long-term period after surgical correction.
Results. The evaluation of systolic and diastolic LV function done from 1,9 to 19.3 (7; 5.7÷12.5) years after surgery showed that Z-score of echocardiographic indicators had been within normal age ranges and had not been associated with age, weight or obstructive pulmonary bloodflow at the time of the TAPVC surgery.
Conclusion. As the result of our study, we did not reveal echocardiographic data showed or confirmed the relationship between intracardiac hemodynamics in utero and early postnatal period and impairment of systolic and diastolic function of the LV myocardium in the late postoperative period.
References
- Morozov A.A., Movsesyan R.R. Hemodynamic aspects of pulmonary and systemic bloodflow in patients with total anomalous pulmonary venous connection. Regional blood circulation and microcirculation. 2019; 18 (1): 24–30 (in Russ.). DOI: 10.24884/1682-6655-2019-18-1-24-30
- Graham T.P. Jr, Jarmanki J.M., Canent R.V. Jr. Left heart volume characteristics with a right ventricular volume overload: total anomalous pulmonary venous connection and large atrial septal defect. Circulation. 1972; 45: 389–9. DOI: 10.1161/01.cir.45.2.389
- Misumi H., Imai Y., Ishihara K., Hoshino S., Sawatari K., Seo K. et al. Pre and postoperative left ventricular volume and function in infants and children with total anomalous pulmonary venous return. Kyobu geka. The Japanese journal of thoracic surgery. 1993; 46 (11): 926–30.
- Marcondes L.D., Galati J.C., Jones B.O., Konstantinov I.E., d'Udekem Y., Brizard C.P., Cheung M.M. Abnormal left ventricular diastolic function at late follow-up after repair of total anomalous pulmonary venous drainage: the impact of altered ventricular loading in utero. J. Thorac. Cardiovasc. Surg. 2014; 148: 238–44. DOI: 10.1016/j.jtcvs.2013.08.045
- Corno A.F. Borderline left ventricle. Eur. J. Cardiothorac. Surg. 2005; 27 (1): 67–73. DOI: 10.1016/j.ejcts.2004.10.034
- Phoon C.K., Silverman N.H. Conditions with right ventricular pressure and volume overload and a small left ventricle: “hypoplastic” left ventricle or simply a squashed ventricle? J. Am. Coll. Cardiol. 1997; 30: 1547–53. DOI: 10.1016/s0735-1097(97)00351-3
- Kobayashi D., Forbes T.J., Delius R.E., Aggarwal S. Amplatzer vascular plug for transcatheter closure of persistent unligated vertical vein after repair of infracardiac total anomalous pulmonary venous connection. Catheter. Cardiovasc. Interv. 2012; 80 (2): 192–8. DOI: 10.1002/ccd.23497
- Hammon J.W. Jr., Bender H.W. Jr., Graham T.R. Jr., Boucek R.J. Jr., Smith C.W., Erath H.G. Jr. Total anomalous pulmonary venous connection in infancy. Ten years' experience including studies of postoperative ventricular function. J. Thorac. Cardiovasc. Surg. 1980; 80 (4): 544–51.
- Nakamura Y., Hoashi T., Nakata T., Shimada M., Ozawa H., Kurosaki K., Ichikawa H. Left ventricular function after repair of totally anomalous pulmonary venous connection. Ann. Thorac. Surg. 2019; 107: 151–6. DOI: 10.1016/j.athoracsur.2018.07.055
- Morozov A.A., Movsesyan R.R., Fedorova N.V., Golubeva M.V., Vasichkina E.S. “Hemodynamic rehabilitation” of the left ventricle at early time after surgical correction of total anomalous pulmonary venous connection in children. Creative Cardiology. 2019; 13 (4): 320–7 (in Russ.). DOI: 10.24022/1997-3187-2019-13-4-320-327
- Levy P.T., Machefsky A., Sanchez A.A., Patel M. D., Rogal S., Fowler S. et al. Reference ranges of left ventricular strain measures by two-dimensional speckle tracking echocardiography in children: a systematic review and meta-analysis. J. Am. Soc. Echocardiogr. 2016; 29 (3): 209–25. DOI: 10.1016/j.echo.2015.11.016
- Koopman L.P., Rebel B., Gnanam D., Menting M.E., Helbing W.A., Boersma E. Reference values for two-dimensional myocardial strain echocardiography of the left ventricle in healthy children. Cardiology in the Young. 2019; 29: 325–37. DOI: 10.1017/S1047951118002378
About the authors
- Aleksandr A. Morozov, Cand. Med. Sci., Cardiovascular Surgeon; ORCID
- Ruben R. Movsesyan, Dr. Med. Sci., Professor, Corresponding Member of Russian Academy of Sciences, Head of Department; ORCID
- Tat’yana L. Vershinina, Head of the Department, Pediatric Cardiologist; ORCID
- Svetlana G. Fetisova, Junior Researcher, Pediatric Cardiologist; ORCID
- Ol’ga A. Kofeynikova, Junior Researcher, Pediatric Cardiologist; ORCID
- Ol’ga L. Peregudina, Pediatric Cardiologist; ORCID
- Egor A. Karev, Functional diagnostics specialist, Cardiologist, Junior Researcher; ORCID
- Aleksander K. Latypov, Cand. Med. Sci., Head of Department; ORCID
- Elena S. Vasichkina, Dr. Med. Sci., Head of the Research Department; ORCID