Abstract
Hypoplastic left heart syndrome (HLHS) – is the most common congenital heart disease (CHD) with univentricular hemodynamics
and, accordingly, one of the most prognostically unfavorable CHD for surgical correction. Mortality in newborns with HLHS tends to 90%, however, it can be reduced by performing double-ventricular correction of the defect, which is possible with sufficient sizes of
the left heart. An increase in blood flow to the left heart in fetuses with HLHS may contribute to the formation of large left structures.
The current review presents a summary of the success of the treatment of fetuses with HLHS by maternal hyperoxygenation
(MH). The effect of MH is to increase the pulmonary blood flow of the fetus and venous return to the left parts of the heart, which contributes
to the formation of large left parts of the heart. MH can also be used as a method for diagnosing intrauterine restriction of an
oval window in children with HLHS, which is important for delivery planning and postnatal management tactics, including determining
the need for an atrioseptostomy immediately after birth.
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About the authors
- Oksana V. Shumakova, Postgraduate, Neonatologist, orcid.org/0000-0002-3627-077X;
-
Elena A. Zelyanina, Postgraduate, Neonatologist, orcid.org/0000-0002-6348-7579;
-
Ekaterina L. Bockeria, Dr. Med. Sc., Professor, Advisor to the Director, Head of Department, Chair Professor, Neonatologist, Pediatric Cardiologist, Anesthesiologist-Intensivist, orcid.org/0000-0002-8898-9612
