Abstract
Objective. To conduct a comparative analysis of the efficacy and safety of inhaled anesthesia (IA) with sevoflurane using a laryngeal mask (LM) and total intravenous anesthesia (TIVA) based on propofol without tracheal intubation, during endovascular operations of congenital heart defects in preschool, school and adolescent children.
Material and methods. A blind randomized prospective study included 290 patients divided into two groups: TIVA (n = 145) and IA (n = 145). Randomization was carried out using the envelope method with a ratio of 1:1.
Results. The hemodynamic profile of the patients in both groups was comparable. The pre-selected tactics of anesthetic support did not change: the TIVA group always had a ready-to-use anesthesia machine with everything necessary for a quick transition to IA or general anesthesia, but it was never necessary to do this, as well as in the IA group, the LM installation took place without technical difficulties and it was not necessary to intubate the trachea to ensure airway patency.
Conclusion. The clinical efficacy of IA and TIVA is comparable in terms of the main measured parameters. IA is more stable, and surgeons perceive it as a more comfortable type of anesthesia, which takes into account their requirements for the absence of hemodynamic disorders and physical activity of the patient.
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About the authors
- Gleb E. Gorbunov, Anesthesiologist-Intensivist; ORCID
- Nikolay A. Solovev, Anesthesiologist-Intensivist; ORCID
- Mariya S. Volodina, Anesthesiologist-Intensivist; ORCID
- Nataliya V. Karakhan, Anesthesiologist-Intensivist; ORCID
- Kakhaber E. Diasamidze, Dr. Med. Sci., Leading Researcher; ORCID
- Mikhail M. Rybka, Dr. Med. Sci., Deputy Director for Anesthesiology and Resuscitation, Head of Department of Anesthesiology, Resuscitation and Intensive Care; ORCID
