Abstract
The trend toward an increase in the premature infants population acutely raises the question of the treatment possibility and efficacy for low birth weight and premature infants with congenital heart disease. These patients are susceptible to many complications, since, in addition to critically low body weight and immature organs and neuro-humoral systems, they have pathological blood circulation caused by congenital heart disease. It is noteworthy, that the risk stratification scales for patients after cardiac surgery do not include features of pregnancy and fetal development. This literature review is devoted to the analysis of perinatal risk factors for the development of unfavorable outcomes in premature infants with congenital heart disease after surgical treatment.
References
- Ohuma E., Moller A.-B., Bradley E., Chakwera S., Hussain-Alkhateeb L., Lewin A. et al. National, regional, and worldwide estimates of preterm birth in 2020, with trends from 2010: a systematic analysis. Lancet. 2023; 402 (10409): 1261–71. DOI: 10.1016/S0140-6736(23)00878-4
- Honein M.A., Kirby R.S., Meyer R.E., Xing J., Skerrette N.I., Yuskiv N. et al. The association between major birth defects and preterm birth. Matern. Child Health J. 2009; 13: 164–75. DOI: 10.1007/s10995-008-0348-y
- Palma A., Morais S., Silva P.V., Pireg A. Congenital heart defects and preterm birth: Outcomes from a referral center. Rev. Port. Cardiol. 2023; 42 (5): 403–10. DOI: 10.1016/j.repc.2022.05.009
- Steurer M.A., Baer R.J., Keller R.L., Oltman S., Chambers C.D., Norton M.E. et al. Gestational age and outcomes in critical congenital heart disease. Pediatrics. 2017; 140: e20170999. DOI: 10.1542/peds.2017-0999
- Abrishamchian R., Kanhai D., Zwets E., Nie L., Cardarelli M. Low birth weight or diagnosis, which is a higher risk?: a meta-analysis of observational studies. Eur. J. Cardiothorac. Surg. 2006; 30: 700–5. DOI: 10.1016/j.ejcts.2006.08.021
- Tomek V., Jicínská H., Pavlícek J., Kovanda J., Jehlicka P., Klásková E. et al. Pregnancy termination and postnatal major congenital heart defect prevalence after introduction of prenatal cardiac screening. JAMA Netw. Open. 2023; 6 (9): e2334069. DOI: 10.1001/jamanetworkopen.2023.34069
- Matthiesen N.B., Henriksen T.B., Agergaard P., Gaynor J.W., Bach C.C., Hjortdal V.E., Østergaard J.R. Congenital heart defects and indices of placental and fetal growth in a nationwide study of 924 422 liveborn infants. Circulation. 2016; 134 (20): 1546–56. DOI: 10.1161/CIRCULATIONAHA.116.021793
- Desmond A., Imany-Shakibai H., Wong D., Kwan L., Satou G., Sklansky M., Afshar Y. Prenatal congenital heart disease and placental phenotypes: preserved neonatal weight despite small placentas. JACC: Adv. 2023; 2 (4): 100383. DOI: 10.1016/j.jacadv.2023.100383
- Moon-Grady A.J. Why would a cardiologist be interested in the placenta? JACC: Adv. 2023; 2 (4): 1–3. DOI: 10.1016/j.jacadv.2023.100403
- Almog B., Shehata F., Aljabri S., Levin I., Shalom-Paz E., Shrim A. Placenta weight percentile curves for singleton and twins deliveries. Placenta. 2011; 32 (1): 58–62. DOI: 10.1016/j.placenta.2010.10.008
- Shehata F., Levin I., Shrim A., Ata B., Weisz B., Gamzu R., Almog B. Placenta/birthweight ratio and perinatal outcome: a retrospective cohort analysis. BJOG. 2011; 118 (6): 741– 7. DOI: 10.1111/j.1471-0528.2011.02892.x
- Bonnet D. Impacts of prenatal diagnosis of congenital heart diseases on outcomes. Transl. Pediatr. 2021; 10 (8): 2241– 9. DOI: 10.21037/tp-20-267
- Lawn J.E., Davidge R., Paul V.K., von Xylander S., de Graft Johnson J., Costello A. et al. Born too soon: care for the preterm baby. Reprod. Health. 2013; 10 (1): S5. DOI: 10.1186/1742-4755-10-S1-S5
- Costello J.M., Pasquali S.K., Jacobs J.P., He X., Hill K.D., Cooper D.S. et al. Gestational age at birth and outcomes after neonatal cardiac surgery: an analysis of the Society of Thoracic Surgeons Congenital Heart Surgery Database. Circulation. 2014; 17; 129 (24): 2511–7. DOI: 10.1161/CIRCULATIONAHA.113.
- Yoon Y.M., Bae S.P., Kim Y.J., Kwak J.G., Kim W.H., Song M.K. et al. New modified version of the Risk Adjustment for Congenital Heart Surgery category and mortality in premature infants with critical congenital heart disease. Clin. Exp. Pediatr. 2020; 63 (10): 395–401. DOI: 10.3345/cep.2019.01522
- Kalfa D., Krishnamurthy G., Duchon J., Najjar M., Levasseur S., Chai P. et al. Outcomes of cardiac surgery in patients weighing <2.5 kg: affect of patient-dependent and independent variables. J. Thorac. Cardiovasc. Surg. 2014; 148 (6): 2499–506.e1. DOI: 10.1016/j.jtcvs.2014.07.031
- Norman M., Håkansson S., Kusuda S., Vento M., Lehtonen L., Reichman B. et al. International Network for Evaluation of Outcomes in Neonates (iNeo) Investigators. Neonatal Outcomes in Very Preterm Infants With Severe Congenital Heart Defects: An International Cohort Study. J. Am. Heart Assoc. 2020; 9 (5): e015369. DOI: 10.1161/JAHA.119.015369
- Steurer M.A., Peyvandi S., Costello J.M., Moon-Grady A.J., Habib R.H., Hill K.D. et al. Association between Z-score for birth weight and postoperative outcomes in neonates and infants with congenital heart disease. J. Thorac. Cardiovasc. Surg. 2021; 162 (6): 1838–47.e4. DOI: 10.1016/j.jtcvs.2021.01.065
- Sochet A.A., Ayers M., Quezada E., Braley K., Leshko J., Amankwah E.K. et al. The importance of small for gestational age in the risk assessment of infants with critical congenital heart disease. Cardiol. Young. 2013; 23: 896–904. DOI: 10.1017/S1047951113001960
- Malik S., Cleves M.A., Zhao W., Correa A., Hobbs C.A.; National Birth Defects Prevention Study. Association between congenital heart defects and small for gestational age. Pediatrics. 2007; 119 (4): e976-82. DOI: 10.1542/peds.2006-2742
- Ghanchi A., Rahshenas M., Bonnet D., Derridj N., LeLong N., Salomon L.J. et al. Prevalence of growth restriction at birth for newborns with congenital heart defects: a population-based prospective cohort study EPICARD. Front. Pediatr. 2021; 9: 676994. DOI: 10.3389/ fped.2021.676994
- Cheung P.Y., Hajihosseini M., Dinu I.A., Switzer H., Joffe A.R., Bond G.Y., Robertson C.M.T. Outcomes of preterm infants with congenital heart defects after early surgery: defining risk factors at different time points during hospitalization. Front. Pediatr. 2021; 8: 616659. DOI: 10.3389/fped.2020.616659
- Goldshtrom N., Vasquez A.M., Chaves D.V., Bateman D.A., Kalfa D., Levasseur S. et al. Outcomes after neonatal cardiac surgery: The impact of a dedicated neonatal cardiac program. J. Thorac. Cardiovasc. Surg. 2023; 165 (6): 2204–11.e4. DOI: 10.1016/j.jtcvs.2022.06.013
- Steurer M.A., Baer R.J., Burke E., Peyvandi S., Oltman S., Chambers C.D. et al. Effect of fetal growth on 1-year mortality in neonates with critical congenital heart disease. J. Am. Heart Assoc. 2018; 7: e009693. DOI: 10.1161/JAHA.118.009693
- Kecskes Z., Cartwright D.W. Poor outcome of very low birthweight babies with serious congenital heart disease. Arch. Dis. Child. Fetal. Neonatal. Ed. 2021; 87 (1): F31–3. DOI: 10.1136/fn.87.1.f31
- Ghanchi A., Derridj N., Bonnet D., Bertille N., Salomon L.J., Khoshnood B. Children born with congenital heart defects and growth restriction at birth: a systematic review and meta-analysis. Int. J. Environ. Res. Public. Health. 2020; 28; 17 (9): 3056. DOI: 10.3390/ijerph17093056
- Cheng H.H., Almodovar M.C., Laussen P.C., Wypij D., Polito A., Brown D.W. et al. Outcomes and risk factors for mortality in premature neonates with critical congenital heart disease. Pediatr. Cardiol. 2011; 32 (8): 1139–46. DOI: 10.1007/s00246-011-0036-3
- Dodge-Khatami J., Dodge-Khatami A., Knudson J.D., Seals S.R., Aggarwal A., Taylor M.B., Salazar J.D. Alternative strategies in newborns and infants with major comorbidities to improve congenital heart surgery outcomes at an emerging programme. Cardiol. Young. 2016; 26 (3): 485–92. DOI: 10.1017/S1047951115000463
- Kopf G.S., Mello D.M. Surgery for congenital heart disease in low-birth weight neonates: a comprehensive statewide Connecticut program to improve outcomes. Conn. Med. 2003; 67 (6): 327–32. PMID: 12956042
- Henmi S., Essa Y., Öztürk M., Tongut A., Desai M., Yerebakan C., d’Udekem Y. Cardiovascular surgery in very low birth weight (≤1500 g) neonates. Eur. J. Cardiothorac. Surg. 2022; 63 (1): ezac552. DOI: 10.1093/ejcts/ezac552
- Dollat C., Vergnat M., Laux D., Stos B., Baruteau A., Capderou A. et al. Critical congenital heart diseases in preterm neonates: is early cardiac surgery quite reasonable? Pediatr. Cardiol. 2015; 36 (6): 1279–86. DOI: 10.1007/s00246-015-1158-9
- Averin K., Ryerson L., Hajihosseini M., Dinu I.A., Freed D.H., Bond G. et al. Infants less than or equal to 2.5 kg have increased mortality and worse motor neurodevelopmental outcomes at 2 years of age after Norwood–Sano palliation. JTCVS. 2023; 14: 417–25. DOI: 10.1016/j. xjon.2023.03.007
About the authors
- Irina Yu. Baryshnikova, Cand. Med. Sci., Researcher; ORCID
- Rena M. Gasanova, Dr. Med. Sci., Head of Perinatal Cardiology Center, Cardiologist, Ultrasound Diagnostician; ORCID
