Abstract
Given the low detection of congenital heart disease (CHD) in the first trimester of pregnancy, and often in the second trimester, and also a high
mortality rate in the postnatal period, there is need to develop new methods for early diagnosis. A large number of works devoted to the development
of additional prognostic methods for the early detection of CHD of fetuses with normal nuchal fold thickness and normal karyotype. Bythe
summary data of world literature the anomalous blood flow in ductus venosus in early pregnancy may be a marker of CHD.
Our abstract represents one clinical CHD observation of a fetus with normal nuchal fold thickness, but with the presence of abnormal blood flow
in the ductus venosus of the fetus in the first trimester of pregnancy.
References
1. Агеева М.И. Состояние кровотока в венозном протоке и нижней полой вене плода во II–III триместрах беременности физиологиче-
ской беременности. Ультразвуковая и функциональная диагностика. 2006; 3: 13–27.
2. Timmerman E., Clur S.A., Pajkrt E., Bilardo C.M. First-trimester measurement of the ductus venosus pulsatility index and the prediction of
congenital heart defects. Ultrasound Obstet. Gynecol. 2010; 36: 668–75.
3. Huisman T.W., Bilardo C.M. Transient increase in nuchal translucency thickness and reversed end-diastolic ductus venosus flow in a fetus
with trisomy 18. Ultrasound Obstet. Gynecol. 1997; 10: 397–9.