Abstract
Introduction. Coarctation of the aorta – a defect of critical neonatal period in the treatment of which are well established and surgical
and endovascular methods. Despite the fact that the method of balloon angioplasty of coarctation of the aorta is used from the end
of the 20th century, there are still conflicting evidence about its use in neonates.
Material and methods. the article presents the experience of balloon angioplasty of coarctation of aorta in newborns and children first
year of life (n=48). Depending on the type of stenosis patients were divided into two groups: group 1 – patients with hypoplastic form
(n=10) and group 2 – membranous form (n=38).
Results. According to angiocardiography gradient of systolic pressure on the narrowing in patients of group 1 amounted to 32.0
(14.0; 36.5) mm Hg (ranged from 3 to 60 mm Hg), the diameter of the aortic isthmus was 4.6 (3.3; 5.0) mm (from 2.8 mm to
6.0 mm), and in patients of group 2 – a gradient of systolic pressure amounted to 40.0 (30.0; 55.0) mm Hg, (ranged from 10 to
94 mm Hg), and the diameter of the isthmus making 3.0 (2.5; 3.9) mm (from 1.5 mm to 6 mm), p=0.01. Hospital mortality was
12.5% (6 patients): intraoperative mortality was 2.1% (1 case), due to the perforation of the wall of the left atrium with the development
of tamponade when performing one-stage follow-up procedure, Rashkind procedure; the mortality in the immediate postoperative
period is 10.4% (5 patients), due to the initial severity of the patients. Non-fatal complications – thrombosis of the common
femoral artery in 3 (6.3%) patients, requiring thrombectomy. In patients of group 1 the diameter of the aortic isthmus increased on
average 1.1 times (4.6 (3.3; 5.5) 5,2 mm vs (4.0; 6.5) mm, p=0.01), and systolic pressure gradient decreased 5.3 times (32.0 (14.0;
36.5) mm Hg vs 6.0 (1.5; 15.0) mm Hg, p=0.01). Among patients of group 2, the diameter of the aortic isthmus increased on average
1.7 times (3.0 (2.5; 3.9) vs 5,1 mm (4.3; 6.4) mm, p=0.01), and the gradient of the systolic pressure decreased by 10 (40.0
(30.0; 55.0) mm Hg vs 4.0 (1.0; 12.5) mm Hg, p=0.01).
Conclusion. The obtained results showed the feasibility and efficacy of balloon angioplasty in the treatment of patients with coarctation
of the aorta. Decrease of systolic pressure gradient on the isthmus, as well as increasing its diameter to allow both groups to consider
balloon angioplasty as a method of choice to stabilize the clinical condition of patients with complex congenital heart disease.
References
- Бокерия Л.А., Туманян М.Р., Абрамян М.А., Андерсон А.Г.,
Левченко Е.Г., Ефремов С.О. Результаты хирургического лечения новорожденных с врожденными пороками сердца
(транспозиция магистральных артерий, атрезия легочной
артерии с дефектом межжелудочковой перегородки) диагностированных пренатально. Детские болезни сердца
и сосудов. 2006; 6: 41–50.
- Бокерия Л.А., Туманян М.Р., Филаретова О.В, Трунина
И.И. Кардиохирургия новорожденных. Новые подходы
к анализу результатов и факторов риска (современное состояние проблемы). Бюллетень НЦССХ им. А.Н. Бакулева
РАМН. 2010; 6: 4–18.
- Бокерия Л.А., Туманян М.Р., Абрамян М.А., Есаян А.А. Обструктивные поражения дуги аорты в сочетании с дефектом
межжелудочковой перегородки у новорожденных: эмбриология, классификация, хирургическая тактика. Детские болезни сердца и сосудов. 2006; 6: 31–6.
- Есаян А.А. Хирургическое лечение новорожденных с врожденной обструктивной патологией дуги аорты в сочетании
с дефектом межжелудочковой перегородки: Автореферат
дис. … канд. мед. наук. М.; 2011.
- Рогова Т.В. Клиника, диагностика и показания к хирургическому лечению коарктации аорты у детей первого года жизни:
Автореф. дис. … канд. мед. наук. М.; 2002.
- Шарыкин А.С. Врожденные пороки сердца. М.: Теремок;
2005: 224–42.
- Алекси-Месхишвили В.В. Хирургическое лечение врожденных пороков сердца у детей первого года жизни: Автореф.
дис. … д-ра мед. наук. М.; 1978.
- Бокерия Л.А., Алекян Б.Г., Пурсанов М.Г. Транслюминальная
баллонная ангиопластика и стентирование коарктации и рекоарктации аорты. В кн.: Бокерия Л.А., Алекян Б.Г. (ред.)
Руководство по рентгенэндоваскулярной хирургии сердца
и сосудов. М.: НЦССХ им. А.Н. Бакулева РАМН; 2008: Т. 2;
215–36.
- Campbell M. Natural history of coarctation of the aorta.
Br. Heart J. 1970; 32: 633–40.
- Lock J.E., Bass J.L., Amplatz K., Fuhrman B.P., Casteneda-
Zuniga W. Balloon dilatation angioplasty of aortic coarctations in
infants and children. Circulation. 1983; 68: 2677–83.
- Ziemer G., Jonas R.A., Perry S.B., Freed M.D., Castaneda A.R.
Surgery for coarctation of the aorta in the neonate. Circulation.
1986; 74: 125–31.
- Rosental E. Coarctation of the aorta from fetus to adult: curable
condition or life long disease process. Heart. 2005; 91:
1495–502.
- Sudarshan C.D., Cochrane A.D., Jun Z.H., Soto R., Brizard C.P.
Repair of coarctation of the aorta in infants weighing less than
2 kilograms. Ann. Thorac. Surg. 2006; 82: 158–63.
- Adjagba P.M., Hanna B., Mirу J., Dancea A., Poirier N.,
Vobecky S. et al. Percutaneous angioplasty used to manage
native and recurrent coarctation of the aorta in infants younger
than 1 year: immediate and midterm results. Pediatr. Cardiol.
2014; 35 (7): 1155–61.
- Rao P.S., Galal O., Smith P.A., Wilson A.D. Five- to nine-year
follow-up results of balloon angioplasty of native aortic coarctation
in infants and children. J. Am. Coll. Cardiol. 1996; 27:
462–70.
- Khyslov G.V. Aortic aneurysms at the site of the repair of coarctation
of the aorta: a review of 48 patients. The society of thoracic
surgeons. Ann. Thorac. Surg. 1996; 61: 935–9.
- Fiore A.C., Fischer L.K., Schwartz T., Jureidini S., Balfour I.,
Carpenter D. et al. Comparison of angioplasty and surgery for
neonatal aortic coarctation. Ann. Thorac. Surg. 2005; 80:
1659–64.
- Al-Ammouri I., Jaradat S., Radwan J. Severe coarctation of the
aorta in a 900 g donor of twin-twin transfusion newborn with
successful repeated transcatheter angioplasty: a case report.
Cardiol. Young. 2015; 25 (2): 394–7.
- Ammar R.I. Balloon angioplasty for native aortic coarctation in
children and infants younger than 12 months: immediate and
medium-term follow-up. J. Invasive Cardiol. 2012; 24 (12):
662–6.
- Dryzek P., Goreczny S., Kopala M. Interventional treatment of
critical coarctation of the aorta in an extremely low birth weight
preterm neonate. Cardiol. Young. 2012; 22 (4): 475–7.
- Алекян Б.Г., Спиридонов А.А., Харпунов В.Ф., Данилов Е.Ю., Тутов Е.Г., Гаджиев А.А. Результаты баллонной
ангиопластики при лечении коарктации и рекоарктации аорты. Грудная и сердечно-сосудистая хирургия. 1996; 6:
144–5.
- Петросян Ю.С., Алекян Б.Г., Саркисова Т.Н., Аржанухина С.Ю. Транслюминальная баллонная вальвулопластика
и ангиопластика в лечении некоторых врожденных пороков
сердца. Вестник АМН СССР. 1989; 10: 40–6.
- Ланг Т.А., Сесик М. Как описывать статистику в медицине.
Аннотированное руководство для авторов, редакторов и рецензентов. Пер. с англ. М.: Практическая медицина; 2011.
- Moore J.W., Vincent R.N., Beekman R.H., Benson L., Bergersen
L., Holzer R. et al. Procedural results and safety of common
interventional procedures in congenital heart disease initial
report from the national cardiovascular data registry. J. Am.
Coll. Cardiol. 2014; 64 (23): 2439–51.
- He L., Liu F., Wu L., Qi C.H., Zhang L.F., Huang G.Y. Percutaneous
balloon angioplasty for severe native aortic coarctation in
young infants less than 6 months: medium- to long-term followup.
Chin. Med. J. (Engl.). 2015; 128 (8): 1021–5.