Abstract
The case has been reported regarding successful transluminal balloon valvuloplasty of aortic valve stenosis in a 5-mounths-old male
child with progressive osseous heteroplasia (POH). It is a rare genetic condition of progressive heterotopic ossification of skin, subcutaneous
fat and deep connective tissue. Progressive osseous heteroplasia is caused by heterozygous inactivating mutations of
GNAS1 – gene. The surgical correction of aortic valve stenosis in infant with POH was carried out in accordance with the medical
management of heterotopic ossification to reduce of perioperative risk and long-term outcomes. As a result, any complications
haven't been on POH for 3 months after surgery. The pressure gradient on aortal valve has had resistant positive dynamics.
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