Results of surgical repair of congenital subaortic stenosisregarding of patient's age

Authors: V.V. Bazylev, D.A. Bofanov, I.E. Chernogrivov, Sh.F. Suleymanov, A.E. Chernogrivov

Company: Federal Center of Cardiovascular Surgery of the Ministry of Health of the Russian Federation, ulitsa Stasova, 6, Penza, 440071, Russian Federation

Cite as: Bazylev V.V., Bofanov D.A., Chernogrivov I.E., Suleymanov Sh.F., Chernogrivov A.E. Results of surgical repair of congenital subaortic stenosis regarding of patient's age. Children’s Heart and Vascular Diseases (Detskie Bolezni Serdtsa i Sosudov). 2018; 15 (2): 92–9 (in Russ.). DOI: 10.24022/1810-0686-2018-15-2-92-99

Received / Accepted: 11.12.2017/18.12.2017

Keywords: subaortic stenosis left ventricular outlet tract

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Abstract

Objective. To analyze long-term results of surgical treatment of congenital subaortic stenosis in children, associated with age.

Material and methods. 46 patients underwent open-heart surgery for subaortic stenosis during the period from 2009 to 2017 in our clinic. Patients were divided into two groups according to their age. The first group included patients below the age of 3 years (n=20), and the second – older than 3 years (n=26). The mean age at the time of surgery was 15.6±4.5 months in the first group and 134.3±15.2 months in the second group.

Results. Clinical follow-up data up to 7 years were obtained for 46 (100%) patients. There were not early and long-term postoperative mortality. Redo open heart procedures were performed in 9 patients. Freedom from reoperations at the time of follow up to 7 years for patients younger than 3 years was 49.7%, for patients older 3 years was 91.2%. A statistically analyze revealed a significantly association between age of patients below 3 years old at the time of surgery (odds ratio (OR) 16.7, confidence interval (CI) 1.86–148.8, p=0.012) and pressure gradient in left ventricular outlet tract at the time of patients discharge from hospital (OR 1.21, CI 1.03–1.21, p=0.006) as a risk factors on the further subaortic reobstruction.

Conclusion. Surgical treatment of subaortic obstruction provides good results at follow-up to 7 years. Nevertheless, restenosis still remains a challenge. There was a correlation established as a risk factor of subaortic reobstruction between the patients’ age at the time of surgery and significant pressure gradient in left ventricular outlet tract after correction.

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About the authors

Bazylev Vladlen Vladlenovich, Dr Med. Sc., Chief Physician, orcid.org/0000-0001-6089-9722;
Bofanov Dmitriy Alekseevich, Cardiovascular Surgeon, orcid.org/0000-0003-0492-8845;
Chernogrivov Igor' Evgen'evich, Dr Med. Sc., Cardiovascular Surgeon, orcid.org/0000-0002-6619-3875;
Suleymanov Shakhriyar Fazailovich, Anesthesiologist-Intensivist, orcid.org/0000-0002-4982-4882;
Chernogrivov Aleksey Evgen'evich, Dr Med. Sc., Head of Department, orcid.org/0000-0002-6207-4799

Chief Editor

Konstantin V. Shatalov
MD, PhD, DSc, Professor
Bakoulev National Medical Research Center for Cardiovascular Surgery

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