Abstract
Objective. We describe method of surgical correction of aortic arch obstruction in newborn with normothermic cerebromyocardial perfusion. Immediate results were analyzed.
Material and methods. Was performed retrospective review of medical records of patients operate in our department from 2014 to 2018. Statistical analysis was performed with Statistical Package for the Social Sciences 26 (IBM corporation, USA).
Results. Sixteen patients were included. Perfusion time was 50 (44–58) minutes, selective cerebromyocardial perfusion time – 27 (20.5–31.5) minutes. Mean minimal temperature during operation was 35.3 ± 0.6 °С. We had no inhospital mortality. Increased myocardial injury and circulatory failure markers were seen 6 and 24 hours after the operation with tendency to decreasing in 48 hours. No signs of brain injury were noted in any patient. Renal injury (defined as peritoneal dialysis requirement) was in 2 (12.5%) patients.
Conclusion. Described method allows to achieve effective brain and myocardial protection for aortic arch obstruction correction in newborn. Kidney injury risk is relatively low.
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About the authors
- Dmitriy A. Bodrov, Cardiovascular Surgeon; ORCID
- Mariya O. Mishina, Resident Physician; ORCID
- Aleksey I. Kim, Dr. Med. Sci., Professor, Head of Department; ORCID
- Konstantin B. Kazantsev, Cand. Med. Sci., Head of Department; ORCID
- Aleksey I. Svalov, Cand. Med. Sci., Head of Department; ORCID
- Evgeniy M. Tarasov, Anesthesiologist; ORCID