Abstract
In newborns with critical aortic coarctation, cardiogenic shock, metabolic acidosis and dysfunction of target organs often occur when the arterial duct is closed. The reaction to prostaglandins can be unpredictable. In the decompensated condition of newborns, the risk of “open” surgical correction of the defect is extremely high, therefore one of the preferred methods is stenting of the isthmus of the aorta. We present our experience of palliative stenting of coarctation in newborns in critical condition. Immediate and early postoperative results are discussed. Aim – to present the immediate and early postoperative results of palliative stenting of critical aortic coarctation in newborns.
Material and methods. We reviewed data on 20 newborns (average age 14 (7.5–26.5) days) who underwent palliative aortic coarctation stenting between 2008 and 2021.
Results. Procedural success was achieved in all patients. Death at the hospital stage occurred in 2 (10%) patients. Multiple organ failure developed in 2 (10%) cases. Paradoxical hypertension was observed in 2 (10%) newborns in the postoperative period. The average follow-up period of patients in the intensive care unit was 5 (4;8.5) days. The duration of artificial lung ventilation is 2.5 (1; 7.5) days.
Conclusion. Primary implantation of a stent as a palliative treatment for critical aortic coarctation is technically feasible in newborns for whom “open” surgery is contraindicated. Stenting of critical aortic coarctation may be an alternative to primary surgical correction.
References
- Wright E.M., Kerr B. RAS-MAPK pathway disorders: important causes of congenital heart disease, feeding difficulties, developmental delay and short stature. Arch. Dis. Child. 2010; 95 (9): 724–30. DOI: 10.1136/adc.2009.160069
- Soynov I.A., Kulyabin Yu.Yu., Gorbatykh A.V., Voytov A.V., Omelchenko A.Yu., Gorbatykh Yu.N. et al. Palliative stenting in a newborn with critical coarctation of the aorta. Circulation Pathology and Cardiac Surgery. 2019; 23 (1): 78–82 (in Russ.). DOI: 10.21688/1681-3472-2019-1-78-82
- Kulyabin Y.Y., Gorbatykh Y.N., Soynov I.A., Nichay N.R., Zubritskiy A.V., Bogachev-Prokophiev A.V. Double arterial cannulation in the critical management of neonatal aortic arch obstruction with closed ductus arteriosus. World J. Pediatr. Congenit. Heart Surg. 2019; 10 (1): 105–8. DOI: 10.1177/2150135118790944
- Bugeja J., Cutajar D., Zahra C., Parascandalo R., Grech V., DeGiovanni J.V. Aortic stenting for neonatal coarctation of the aorta – when should this be considered? Images Paediatr. Cardiol. 2016; 18 (3): 1–4.
- Sreeram I., Sreeram N., Bennink G. Palliative stent implantation for coarctation in neonates and young infants. Ann. Pediatr. Cardiol. 2012; 5 (2): 145–50. DOI: 10.4103/0974-2069.99616
- Gilboa S.M., Salemi J.L., Nembhard W.N., Fixler D.E., Correa A. Mortality resulting from congenital heart disease among children and adults in the United States, 1999 to 2006. Circulation. 2010; 122 (22): 2254–63. DOI: 10.1161/CIRCULATIONAHA.110.947002
- Yucel I.K., Cevik A., Bulut M.O., Dedeoglu R., Demir I.H., Erdem A., Celebi A. Efficacy of very low-dose prostaglandin E1 in duct-dependent congenital heart disease. Cardiology Young. 2015; 25 (1): 56–62. DOI: 10.1017/S1047951113001522
- Alhussin W., Verklan M.T. Complications of long-term prostaglandin E1 use in newborns with ductal-dependent critical congenital heart disease. J. Perinat. Neonatal Nurs. 2016; 30 (1): 73–9. DOI: 10.1097/JPN.0000000000000152
- Rzaeva K.A., Soynov I.A., Gorbatykh A.V., Kulyabin Yu.Yu., Voitov A.V., Ivantsov S.M. et al. Critical coarctation of the aorta: diagnostic capabilities and methods of surgical treatment of aortic coarctation in newborns. Circulation Pathology and Cardiac Surgery. 2020; 24 (2): 46–62 (in Russ.). DOI: 10.21688/1681-3472-2020-2-46-62
- Gaies M.G., Gurney J.G., Yen A.H., Napoli M.L., Gajarski R.J., Ohye R.G. et al. Vasoactive-inotropic score as a predictor of morbidity and mortality in infants after cardiopulmonary bypass. Pediatr. Crit. Care Med. 2010; 11: 234–8. DOI: 10.1097/pcc.0b013e3181b806fc
- Soni M., Piggott K.D., DeCampli W., Ramirez J., Pourmoghadam K., Fakioglu H. et al. Are we overdiagnosing acute kidney injury in pediatric patients following cardiac surgery? World J. Pediatr. Congenit. Heart Surg. 2015; 6 (4): 496–501. DOI: 10.1177/2150135115593129
- Arfi A.M., Galal M.O., Kouatli A., Baho H., Abozeid H,, Al Ata J. Stent angioplasty for critical native aortic coarctation in three infants: up to 15-year follow-up without surgical intervention and review of the literature. Pediatr. Cardiol. 2018; 39: 1501–13. DOI: 10.1007/s00246-018-1922-8
- Alekyan B.G., Pursanov M.G., Kim A.I., Berishvili D.O., Grigoryan A.M., Chuvarayan G.A. CA stenting in critically ill neonates. The Bulletin of Bakoulev Center. Cardiovascular Diseases. 2016; 17 (S3): 70a (in Russ.).
- Peters B., Ewert P., Berger F. The role of stents in the treatment of congenital heart disease: Current status and future perspectives. Ann. Pediatr. Card. 2009; 2: 3–23. DOI: 10.4103/0974- 2069.52802
- Zartner P., Cesnjevar R., Singer H., Weyand M. First successful implantation of a biodegradable metal stent into the left pulmonary artery of a preterm baby. Cathet. Cardiovasc. Interv. 2005; 66: 590–4. DOI: 10.1002/ccd.20520
- Al-Ata J., Arfi A.M., Hussain A., Kouatly A., Galal M.O. Stent angioplasty: an effective alternative in selected infants with critical native aortic coarctation. Pediatr. Cardiol. 2007; 28 (3): 183–92. DOI: 10.1007/s00246-006-0074-4
- Gorenflo M., Boshoff D.E., Heying R., Eyskens B., Rega F., Meyns B., Gewillig M. Bailout stenting for critical coarctation in premature/critical/complex/early recoarcted neonates. Catheter. Cardiovasc. Interv. 2010; 75 (4): 553–61. DOI: 10.1002/ccd.22328
- González-Calle A., Guillén-Rodríguez I., Coserria-Sánchez F. Timing of surgical repair of the stented aortic arch and coarctation in neonates. Cardiol. Young. 2022; 1–2. DOI: 10.1017/S1047951122001445
- Golden A.B., Hellenbrand W.E. Coarctation of the aorta: stenting in children and adults. Catheter. Cardiovasc. Interv. 2007; 69 (2): 289–99. DOI: 10.1002/ccd.21009
- Reddy V.M., McIlhenney D.B., Sagrado T., Parry A.J., Teitel D.F., Hanley F.L. Results of 102 cases of complete repair of congenital heart defects in patients weighing 700 to 2500 grams. J. Thorac. Cardiovasc. Surg. 1999; 117: 324–31. DOI: 10.1016/s0022-5223(99)70430-7
- Moosmann J., Purbojo A., Eder S., Dittrich S. Case report: trans-axillary artery access for rescue stent implantation in an infant with retrograde non-passable aortic coarctation. Front. Pediatr. 2021; 9: 625011. DOI: 10.3389/fped.2021.625011
About the authors
- Kseniya A. Rzaeva, Postgraduate student; ORCID
- Il'ya A. Soynov, Cand. Med. Sci., Cardiovascular Surgeon; ORCID
- Artem V. Gorbatykh, Cand. Med. Sci., Cardiovascular Surgeon, Head of the Research Laboratory
of Interventional Surgery; ORCID
- Aleksey N. Arkhipov, Cand. Med. Sci., Cardiovascular Surgeon, Head of the Department; ORCID
- Aleksey V. Voitov, Cand. Med. Sci., Cardiovascular Surgeon; ORCID
- Yuriy Yu. Kulyabin, Cand. Med. Sci., Cardiovascular Surgeon; ORCID
- Yuriy N. Gorbatykh, Dr. Med. Sci., Professor, Cardiovascular Surgeon; ORCID
- Aleksandr V. Bogachev-Prokophiev, Dr. Med. Sci., Cardiovascular Surgeon, Director; ORCID